Salmon DNA
Salmon DNA (PDRN) uses purified polynucleotides to support skin quality and tissue repair, and is planned as a course of sessions.
- Duration
- 40 min
- Area
- Face
- Planning
- Course of 3–4 sessions
What salmon DNA (PDRN) is
The active substance in the treatment known as salmon DNA is polydeoxyribonucleotide, or PDRN. It consists of short polynucleotide chains produced by purifying and fragmenting DNA obtained from the reproductive cells of salmon.
Salmon is the chosen source because the resulting polynucleotide sequences are highly similar to human sequences, which improves biocompatibility. Removing residual protein during purification is the decisive step in reducing the risk of an immune response.
How it differs from filler
This is the point most often confused. PDRN is not a filler and does not create volume. Its target is the quality of the skin: its capacity to hold water, tissue quality, and support for repair processes. In an area with marked volume loss it will not on its own produce the expected result, and in that situation it is assessed alongside filler, or separately.
Where it is considered
- The face generally, for skin quality
- Areas of thin, delicate skin such as around the eyes
- Neck and décolletage
The course
PDRN is given as a course. Typically three to four sessions are planned two to three weeks apart. The effect is judged not after a single session but in the weeks following the completed course, so expecting a rapid change after the first appointment is not realistic.
When the result becomes noticeable
The effect of PDRN is not immediate. Because the process it targets works at tissue level, the change is usually noticed over the later weeks of the course. Seeing no obvious difference straight after the first session is expected and does not mean the treatment is not working.
Once the course is complete, maintenance sessions can be planned at intervals decided individually. How often they are repeated depends on how your skin responds and on the goal.
Safety and when it is not appropriate
A history of allergy to fish or seafood is particularly important here and must be mentioned at the consultation. Active infection at the site, pregnancy and breastfeeding are barriers to treatment. Autoimmune conditions and current medications require separate assessment.
Transient redness, mild swelling and small bruises at the injection points are expected effects and settle quickly.
FAQ
Can it be used if I am allergic to fish?
A history of fish or seafood allergy must be raised at the consultation. Suitability is then assessed separately and, if needed, an alternative plan is proposed.
Does salmon DNA replace filler?
No. PDRN does not create volume; it targets skin quality. In an area with volume loss it does not do the same job as filler, though the two can be planned together.
Treatment information is general and does not replace a medical examination. Indications, contraindications, expected response and session planning are discussed during consultation.